Anticholinesterase toxicity

From anticholinesterase toxicity to Alzheimer's disease: important interactions of cholinergic and NMDA receptor systems.

The article highlighted in this issue is "Dizocilpine Improves Beneficial Effects of Cholinergic Antagonists in Anticholinesterase-Treated Mice," by Andrzej Dekundy, Rafal M. Kaminski, and Waldemar A. Turski (pp. 289-295). It explores the relationship between cholinergic and N-methyl-D-aspartate (NMDA) receptors as mediators of anticholinesterase toxicity. The following review summarizes these ...

TOXICOLOGICAL HIGHLIGHT From Anticholinesterase Toxicity to Alzheimer’s Disease: Important Interactions of Cholinergic and NMDA Receptor Systems

The article highlighted in this issue is “Dizocilpine Improves Beneficial Effects of Cholinergic Antagonists in Anticholinesterase-Treated Mice,” by Andrzej Dekundy, Rafal M. Kaminski, and Waldemar A. Turski (pp. 289–295). It explores the relationship between cholinergic and N-methyl-D-aspartate (NMDA) receptors as mediators of anticholinesterase toxicity. The following review summarizes these ...

Anticholinesterase activity of bufotenine.

Anticholinesterase and antioxidant constituents from Gloiopeltis furcata.

Activity-directed isolation of the ethyl acetate, methylene chloride and n-hexane fractions of Gloiopeltis furcata resulted in the isolation of 18 compounds. Their structures were elucidated as 2-(3-hydroxy-5-oxotetrahydrofuran-3-yl)acetic acid (1), glutaric acid (2), succinic acid (3), nicotinic acid (4), (E)-4-hydroxyhex-2-enoic acid (5), cholesterol (6), 7-hydroxycholesterol (7), uridine (8)...

Assessment of Anticholinesterase Toxicity, Oxidative Stress and Antioxidant Status in Carbamate and Organophosphorus Pesticides- Exposed Agricultural Workers

Among the numerous pesticides, anticholinesterase compounds are widely used. Their toxicity induced by cholinesterase inhibition at the synapses and neuromuscular junctions, leading to neurological disorders. Inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) has been used as sensitive biomarkers for pesticides exposure. In the present study, AChE and BuChE levels were ...